Saturday, 28 June 2025

๐Ÿฉบ"Surgical Protocols & HIV: A Clinical Guide to Safety and Post-Exposure Measures for Surgeons"

 

๐Ÿฉบ"Surgical Protocols & HIV: A Clinical Guide to Safety and Post-Exposure Measures for Surgeons"


๐Ÿ”ท Introduction

Operating on HIV-positive patients requires enhanced vigilance. This blog provides an in-depth medical framework — pre-op, intra-op, and post-op — for infection control, exposure management, and medico-legal safety, ensuring both patient care and surgeon safety.


๐Ÿ›ก️ 1. Pre-Surgical Precautions

a. Universal Precaution

  • Treat all patients as potentially infectious.

  • Use double gloves, face shields, and impermeable gowns.

  • Prepare surgical staff about HIV transmission risks (0.3% per needlestick).

๐Ÿ’Š b. Medication for High-Risk Exposure Anticipation (Optional)

  • If patient is known HIV+ with high viral load, some high-risk centers begin PrEP for surgical team prior to high-risk exposure.

  • Tenofovir Alafenamide 25mg + Emtricitabine 200mg  (1 tab before one day of procedure, 2 tab that day procedure done , 1 tab third day of procedure ) may be considered for continuous high-risk professionals. 


๐Ÿ”ช 2. During Surgery

๐Ÿงท a. Instrument Handling

  • Use blunt suture needles, needle holders, and no-touch technique.

  • Never pass sharps hand-to-hand — use a tray.

๐Ÿฉธ b. Team Management

  • Limit personnel in the OT.

  • Assign a trained assistant to watch for protocol breaches.


๐Ÿšจ 3. What If An Accident Happens? (Exposure Response)

๐Ÿฉป a. Types of Exposures

  • Percutaneous Injury (Needlestick)

  • Mucosal Contact (Eye, Mouth)

  • Non-intact skin exposure

⏱️ b. Immediate First Aid

  • Needlestick: Let it bleed, wash with soap and water.

  • Mucosa: Rinse with saline.

  • Skin: Wash area thoroughly.

๐Ÿ’Š c. Start PEP Within 2 Hours

  • Recommended 28-day PEP regimen:

    • Tenofovir DF (300 mg) + Emtricitabine (200 mg) + Dolutegravir (50mg)  – once daily for 28 day

    •                                                               OR 

    • Tenofovir AF (25 mg) + Lamivudine (300 mg) + Dolutegravir (50mg)  – once daily for 28 day


๐Ÿงช 4. Follow-Up Protocol

  • Baseline HIV, HBsAg, HCV testing

  • Follow-up HIV tests at 6 weeks, 3 months, and 6 months

  • Monitor for PEP side effects (nausea, liver enzymes, renal function)


๐Ÿ“ 5. Documentation & Reporting

  • File incident report immediately.

  • Document time, type of exposure, patient status, and PEP initiation.

  • Notify hospital infection control committee.


⚕️ 6. Legal and Ethical Responsibility

  • Maintain confidentiality of both patient and surgeon.

  • Inform surgeon about right to PEP and counseling.

  • Record consent and disclosure where required.


๐Ÿง  Conclusion: Safety Is Systematic, Not Situational

Treat every surgery as a potential exposure. Use universal precautions, stay prepared for exposure, and act quickly in emergencies. PEP is most effective within 2 hoursdo not delay.


๐Ÿท️ medicine require helpline number 9637531539 and 9421704106

๐Ÿฉบ Pre-Exposure and Post-Exposure Prophylaxis (PrEP & PEP): Complete Guide for Healthcare and High-Risk Settings

 


๐Ÿฉบ Pre-Exposure and Post-Exposure Prophylaxis (PrEP & PEP): Complete Guide for Healthcare and High-Risk Settings

Author: BJ (Health Blogger)
Category: Medical Awareness | Infectious Diseases
Published on: 28 June 2025


๐Ÿงฌ Introduction

In a world where healthcare workers, lab technicians, and even the general public face risk of exposure to serious infections like HIV, Hepatitis B/C, and other blood-borne or sexually transmitted diseases — preventive care becomes critically important.

That's where Pre-Exposure Prophylaxis (PrEP) and Post-Exposure Prophylaxis (PEP) come into play.

These are preventive medical strategies used before or after potential exposure to an infection to reduce the risk of acquiring that infection.


๐Ÿ“Œ What is Pre-Exposure Prophylaxis (PrEP)?

PrEP stands for Pre-Exposure Prophylaxis — it is a method where a person takes medication before being exposed to a virus, especially HIV, to prevent infection.

๐Ÿงช Used For:

  • Preventing HIV infection in high-risk individuals.

  • Preventing Hepatitis B in non-immune persons.

๐Ÿ‘ฅ Who Should Use PrEP?

  • People with a partner who is HIV positive.

  • Health care workers at high risk.

  • Individuals with multiple sexual partners.

  • Injection drug users.

  • People who engage in unprotected sex.

๐Ÿ’Š Common Medicines for PrEP (for HIV):

Medicine NameDrug CombinationNotes
Tab. Tavin-EM     Tenofovir disoproxil + Emtricitabine               Once daily oral pill
Tab. Emtaf             Tenofovir alafenamide + EmtricitabineNot approved for vaginal sex

Effectiveness: PrEP reduces the risk of getting HIV from sex by 99% and from injection drug use by 74%when taken daily.


๐Ÿ“Œ What is Post-Exposure Prophylaxis (PEP)?

PEP stands for Post-Exposure Prophylaxis — taking medication after potential exposure to prevent infection from viruses like HIV, Hepatitis B/C.

๐Ÿ’‰ Used For:

  • Healthcare workers after needle-stick injuries.

  • Accidental exposure to HIV-infected blood.

  • Unprotected sex with someone who may be HIV-positive.

  • Sexual assault victims.

  • Shared needles.

๐Ÿ•’ Timing is Critical:

  • Must be started within 72 hours of exposure.

  • The sooner, the better — ideally within 2 hours.

๐Ÿ’Š Common PEP Regimen (for HIV):

DurationMedicine NameCombination brand name
28 days
Tenofovir alafenamide 25mg + Emtricitabine 200mg+ Dolutegravir 50mg 

Tab Spegra 
28 days
Tenofovir disoproxil 300mg + Lamivudine 300mg + Dolutegravir 50mg


Tab Viropil 

Important: Complete 28-day course even if tests are negative.


๐Ÿฉป PEP for Hepatitis B

SituationAction
Source is HBsAg positive, person not vaccinatedAdminister HBIG + Start full HBV vaccine series immediately
Source unknown or low riskStart vaccine series if unvaccinated
Person vaccinated but non-responderGive HBIG x2 doses, or HBIG + revaccinate

๐Ÿ”ฌ PEP for Hepatitis C (HCV)

  • No effective PEP currently available.

  • Close follow-up and monitoring is recommended.

  • Direct-acting antivirals (DAAs) are used after diagnosis, not as prophylaxis.


๐Ÿ’ก Practical Examples:

SituationProphylaxis UsedWhen to Start
Doctor gets needle prick from HIV+ patientPEP for HIVWithin 2 hours
Nurse exposed to hepatitis B-infected bloodHBIG + HBV vaccineImmediately
Person in high-risk sexual relationshipPrEP for HIVDaily, before exposure
Healthcare student assisting in surgeriesPrEP (optional)Continuous during risk

⚠️ Side Effects and Monitoring

Common Side Effects:

  • Nausea, fatigue, headache

  • Mild liver or kidney function changes

Monitoring Required:

  • HIV test before starting PrEP or PEP

  • Kidney function (Creatinine)

  • Hepatitis B/C testing

  • Pregnancy test (in females of childbearing age)


✅ Summary Checklist

TopicPrEPPEP
UseBefore exposureAfter exposure
TimeDailyWithin 72 hours
DurationOngoing28 days
TargetHigh-risk peopleEmergency exposure cases
Effectiveness99% (HIV)High if started early

๐Ÿ“ข Final Note

PrEP and PEP are powerful tools in protecting healthcare workers, lab technicians, and the general public from potentially life-threatening infections.

Every doctor, surgeon, nurse, and even informed citizen should know:

  • When to use it,

  • What to take,

  • And how to act fast in emergency situations.


๐Ÿ™‹ Need for medicine help line number 9637531539 and 9421704106